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KMID : 1155520220170020228
Anesthesia and Pain Medicine
2022 Volume.17 No. 2 p.228 ~ p.234
Two cases of late-onset cardiovascular toxicities after a single injection of local anesthetics during supraclavicular brachial plexus block - A report of two cases -
Kim Ji-Yeon

Park Beom-Il
Heo Min-Hee
Kim Kyoung-Woo
Lee Sang-Il
Kim Kyung-Tae
Choe Won-Joo
Park Jang-Su
Kim Jun-Hyun
Abstract
Background: Local anesthetics systemic toxicity (LAST) is a grave complication of regional anesthesia that usually occurs immediately after local anesthetics injection. Here, we report on rare late-onset toxicity cases after supraclavicular brachial plexus blocks.

Case: Two patients underwent surgery for radius fractures. We used lidocaine 100 mg and ropivacaine 150 mg for blocking and infused dexmedetomidine for intraoperative sedation. The 63-year-old male patient¡¯s blood pressure dropped to 87/60 mmHg after 3 h 15 min after blocking. Ventricular fibrillation occurred 10 min later. After five defibrillations, electrocardiography showed ventricular tachycardia that was normalized through one cardioversion. The 54-year-old female patient¡¯s heart rate decreased to 35 beats/min 2 h 30 min after blocking. Her vital signs returned to normal after administering atropine, ephedrine, epinephrine, and lipid emulsion.

Conclusions: Physicians should remember that LAST may occur long after local anesthetic injection and be aware of factors that may adversely affect the course of LAST.
KEYWORD
Adverse effects, Brachial plexus block, Lidocaine, Local anesthetic, Ropivacaine, Toxicity
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